This study examined the effects of intermittent hypoxic training (IHT) on skeletal muscle monocarboxylate lactate transporter (MCT) expression and anaerobic performance in trained athletes. Cyclists were assigned to two interventions, either normoxic (N; n = 8; 150 mmHg PIO2) or hypoxic (H; n = 10; ∼3000 m, 100 mmHg PIO2) over a three week training (5×1 h-1h30.week-1) period. Prior to and after training, an incremental exercise test to exhaustion (EXT) was performed in normoxia together with a 2 min time trial (TT). Biopsy samples from the vastus lateralis were analyzed for MCT1 and MCT4 using immuno-blotting techniques. The peak power output (PPO) increased (p<0.05) after training (7.2% and 6.6% for N and H, respectively), but VO2max showed no significant change. The average power output in the TT improved significantly (7.3% and 6.4% for N and H, respectively). No differences were found in MCT1 and MCT4 protein content, before and after the training in either the N or H group. These results indicate there are no additional benefits of IHT when compared to similar normoxic training. Hence, the addition of the hypoxic stimulus on anaerobic performance or MCT expression after a three-week training period is ineffective.
展开▼
机译：这项研究检查了间歇性低氧训练（IHT）对训练有素的运动员骨骼肌单羧酸酯乳酸盐转运蛋白（MCT）的表达和无氧运动的影响。在为期三周的训练（5×1 h-1h30）中，骑自行车者被分配了两种干预措施，即常氧（N; n = 8; 150 mmHg PIO2）或低氧（H; n = 10;〜3000 m，100 mmHg PIO2）。第1周）。在训练前后，在常氧状态下进行了一项关于疲劳的增量运动测试（EXT），并进行了2分钟的时间试验（TT）。使用免疫印迹技术分析了来自股外侧肌的活检样品的MCT1和MCT4。训练后的峰值功率输出（PPO）增加（p <0.05）（N和H分别为7.2％和6.6％），但VO2max没有明显变化。 TT中的平均功率输出显着提高（N和H分别为7.3％和6.4％）。 N组或H组训练前后，MCT1和MCT4蛋白含量均无差异。这些结果表明，与类似的常氧训练相比，IHT没有其他好处。因此，在三周的训练期后，在无氧运动或MCT表达上添加低氧刺激无效。
展开▼
